Cough Monitoring
Objective Cough Monitoring for Any Study Design
Capture objective, real-world cough burden with flexible monitoring solutions designed around your protocol, endpoint strategy, and participants.
Strados for Cough Monitoring
Objective cough monitoring built for clinical research
Strados delivers objective, real-world cough monitoring for clinical trials. Our wearable solutions capture cough burden continuously in daily life, supported by configurable analysis and a traceable evidence chain.
- Objective cough frequency, bouts, and intensity
- Continuous, real-world capture in daily life
- Configurable analysis for any study design
- Retained source audio for a traceable evidence chain
2.2M+
Coughs captured
74M+
Breaths captured
2,100+
Patients monitored
258
Clinical sites
Product Suite
Choose the right cough monitoring device for your study
RESP® Biosensor
High-fidelity, clinical-grade cough monitoring
Designed to capture precise, high-quality cough data when measurement accuracy and signal fidelity are essential, providing greater insight into cough burden.
Best for: Primary endpoints, secondary endpoints, and multidimensional cough monitoring beyond frequency.
Two FDA 510(k) clearances and CE marked.
Learn More
RESP® Watch
Low-friction, multi-day cough monitoring
A familiar form factor designed for easy deployment, particularly well suited for capturing cough over longer, multi-day monitoring periods.
Best for: Subject screening, feasibility studies, population studies, and exploratory endpoints or substudies.
How it works
From cough capture to endpoint-ready data
Capture cough and related respiratory data, securely transfer recordings to the Strados Cloud, and select the analysis approach that fits your study.
Step 1
Capture
Capture cough, respiratory sounds, and related physiological measures during daily life.
Step 2
Securely transfer
Encrypted data securely syncs through the companion device.
Human annotation
Automated annotation
Step 3
Analyze in the Strados Cloud
Configured around the study's endpoints, volume, and evidence requirements.
Step 4
Deliver subject reports
Receive detailed, structured reporting on cough, respiratory sounds, and related physiological data.
Step 1
Capture
Capture cough, respiratory sounds, and related physiological measures during daily life.
Step 2
Securely transfer
Encrypted data securely syncs through the companion device.
Human annotation
Automated annotation
Step 3
Analyze in the Strados Cloud
Configured around the study's endpoints, volume, and evidence requirements.
Step 4
Deliver subject reports
Receive detailed, structured reporting on cough, respiratory sounds, and related physiological data.
Built around your study
Objective cough measurement across the clinical development lifecycle
Configure cough monitoring around your protocol, population, endpoint strategy, and required monitoring duration.
Primary endpoints
24-hour cough frequency supported by gold-standard human cough annotation for regulatory-grade evidence.
Secondary endpoints
Support multidimensional cough endpoints beyond frequency, including cough bouts, intensity, and day/night patterns.
Exploratory endpoints and substudies
Improve understanding of cough burden and quality of life in respiratory studies such as IPF, asthma, COPD, and bronchiectasis.
Feasibility and proof-of-concept studies
Evaluate cough patterns and establish endpoint parameters before larger studies.
Real-world evidence
Capture cough burden during daily life, outside the limits of scheduled site assessments.
See the full picture of cough burden
Capture multiple dimensions of cough burden, including lung sounds and multi-day patterns, to better understand when cough occurs, how it changes, and how it affects participants' daily lives.
Cough frequency
Track coughs per hour or across predefined monitoring periods.
Cough bouts
Understand how cough events cluster over time.
Day and night patterns
Evaluate changes during waking and sleeping periods.
Cough sound intensity
Add context beyond frequency alone.
Lung sounds
Capture cough and wheeze alongside cough frequency for a richer respiratory picture.
Actigraphy, vitals and sleep
Explore how cough relates to daily activity, rest, and physiological signals.
Multi-day cough frequency
Representative monitoring window
Intelligence Advantage
Flexible Cough Analysis to Fit Your Study
Strados offers both manual gold-standard cough annotation by trained analysts and automated machine-learning detection with CoughCheck™, plus hybrid approaches that combine the two. Configure the analysis to fit your study's endpoints, volume, budget, and regulatory requirements, with retained source audio creating a traceable evidence chain from capture through final reporting.
Learn about the Intelligence AdvantageGold-standard annotation
Trained analysts provide expert, endpoint-critical cough review for regulatory-grade evidence.
CoughCheck™ automated detection
Machine-learning cough detection trained on more than 200,000 coughs for high-volume screening.
Hybrid approaches
Combine automated detection with expert review to balance speed, cost, and rigor for your study.
Retained source audio
Reviewable evidence is preserved for traceability and audit readiness from capture through reporting.
Objective cough monitoring across respiratory research
Support endpoint development and treatment evaluation across a range of respiratory conditions and research applications.
Indications represent research applications and do not imply that every measurement has been validated as a primary endpoint in every condition.
Publications
Clinical evidence for cough monitoring
Cough Detection Performance of the CoughCheck Algorithm in Subjects with Subacute Cough
Poster Presentation, American Thoracic Society, 2025
Objective Cough Monitoring Detects More Patients with Cough Than Patient Self-Reporting
Poster Presentation, American Cough Conference, 2023
Results of Clinical Performance Testing in Chronic Lung Diseases
Poster Presentation, American Thoracic Society, 2022
The Strados Remote Electronic Stethoscope Platform: a novel wearable remote auscultation system
Poster Presentation, American Thoracic Society, 2020
Resources
Explore more Strados cough resources
Resource Hub
Browse resources covering objective cough measurement, digital endpoints, and respiratory acoustic analysis.
Visit the Resource HubKey Cough Resource
Read our Cough Endpoint & Validation Guidance for an overview of FDA validation requirements for cough monitoring.
Read the Cough Validation GuidanceeCOA
Pair cough monitoring with Strados eCOA to capture patient-reported symptoms alongside objective cough data for a more complete view of treatment response.
Explore eCOAMeet the team behind our cough expertise
Our clinical, regulatory, and data-science specialists partner with sponsors from protocol design through analysis.
Meet our TeamReady to objectively measure cough burden in your study?
Tell us about your program, and we'll help you design the right cough monitoring and endpoint strategy.
Design a Study →
